Ronald T Acton Selected Research

Hemochromatosis (Bronze Diabetes)

6/2022	HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity.
1/2017	Diabetes in HFE Hemochromatosis.
12/2015	HFE gene: Structure, function, mutations, and associated iron abnormalities.
1/2014	Diabetes in first-degree family members: a predictor of type 2 diabetes in 159 nonscreening Alabama hemochromatosis probands with HFE C282Y homozygosity.
7/2013	Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.
1/2013	Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients from three geographically distant areas.
4/2012	Increased risk of death from iron overload among 422 treated probands with HFE hemochromatosis and serum levels of ferritin greater than 1000 μg/L at diagnosis.
1/2012	Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.
3/2011	Genome-wide association study identifies genetic loci associated with iron deficiency.
11/2010	Longer survival associated with HLA-A03, B14 among 212 hemochromatosis probands with HFE C282Y homozygosity and HLA-A and -B typing and haplotyping.

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Ronald T Acton Research Topics

Disease

38	Hemochromatosis (Bronze Diabetes) 06/2022 - 10/2002
37	Iron Overload 06/2022 - 02/2003
7	Fibrosis (Cirrhosis) 06/2022 - 01/2005
6	Infections 01/2020 - 07/2003
5	Insulin Resistance 01/2018 - 01/2005
4	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 01/2016
4	Common Variable Immunodeficiency 05/2017 - 06/2003
4	Hyperferritinemia 08/2008 - 04/2007
3	Hypersensitivity (Allergy) 01/2020 - 01/2016
3	Iron Deficiencies 07/2013 - 03/2011
3	Cardiomyopathies (Cardiomyopathy) 04/2012 - 07/2002
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 03/2015
2	Hypertrophy 03/2016 - 01/2016
2	Hepatomegaly 03/2016 - 01/2016
2	Diabetes Mellitus 01/2016 - 03/2015
2	Hypothyroidism 01/2016 - 01/2016
2	Hepatitis 01/2014 - 07/2006
2	Liver Failure 04/2012 - 07/2009
2	Siderosis 04/2012 - 07/2009
2	Liver Diseases (Liver Disease) 08/2007 - 07/2006
2	Anemia 03/2006 - 11/2003
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Hepatitis B 01/2018
1	Fibromyalgia (Fibrositis) 05/2017
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 05/2017
1	Fatigue 05/2017
1	Type 2 Diabetes Mellitus (MODY) 01/2017
1	Urinary Tract Infections (Urinary Tract Infection) 01/2016
1	Non-alcoholic Fatty Liver Disease 01/2014
1	Joint Diseases (Joint Disease) 01/2014
1	Liver Neoplasms (Liver Cancer) 04/2012
1	Wounds and Injuries (Trauma) 10/2009
1	Soft Tissue Infections 10/2009
1	Portal Hypertension 05/2009
1	Granuloma 05/2009
1	Liver Cirrhosis (Hepatic Cirrhosis) 05/2009
1	Chronic Renal Insufficiency 04/2009
1	Hemorrhage 04/2009
1	Confusion (Bewilderment) 11/2007
1	Inflammation (Inflammations) 01/2005
1	Coronary Disease (Coronary Heart Disease) 01/2005
1	Multiple Endocrine Neoplasia Type 2b (MEN 3) 01/2005
1	Melanoma (Melanoma, Malignant) 08/2004
1	Hemoglobinopathies 11/2003
1	Thalassemia 11/2003
1	Chronic Hepatitis C 11/2003
1	Vibrio vulnificus infection 09/2003
1	IgA Deficiency 07/2003
1	Heart Failure 07/2002

Drug/Important Bio-Agent (IBA)

31	IronIBA 06/2022 - 02/2003
24	Ferritins (Ferritin)IBA 06/2022 - 01/2005
16	Transferrin (beta 2 Transferrin)IBA 06/2022 - 01/2005
11	HLA-A Antigens (HLA-A)IBA 06/2022 - 10/2002
6	HLA Antigens (Human Leukocyte Antigens)IBA 06/2022 - 01/2005
6	Immunoglobulin G (IgG)IBA 01/2020 - 06/2003
5	Aspartate Aminotransferases (Aspartate Transaminase)IBA 06/2022 - 04/2012
4	DNA (Deoxyribonucleic Acid)IBA 01/2012 - 02/2003
3	Immunoglobulin M (IgM)IBA 01/2020 - 07/2003
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 01/2016
3	Alanine (L-Alanine)FDA Link 03/2016 - 04/2012
3	metal transporting protein 1 (ferroportin)IBA 09/2007 - 11/2003
2	Immunoglobulin A (IgA)IBA 01/2020 - 01/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2016
2	Immunoglobulins (Immunoglobulin)IBA 05/2017 - 07/2003
2	C-Reactive ProteinIBA 03/2016 - 01/2016
2	Ethanol (Ethyl Alcohol)IBA 01/2014 - 11/2003
1	Polysaccharides (Glycans)IBA 01/2020
1	23-valent pneumococcal capsular polysaccharide vaccineIBA 01/2020
1	HepcidinsIBA 01/2019
1	Insulin (Novolin)FDA Link 01/2018
1	Immunoglobulin IsotypesIBA 05/2017
1	HLA-A29 antigenIBA 05/2017
1	Hemochromatosis ProteinIBA 12/2015
1	Alanine Transaminase (SGPT)IBA 01/2014
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2010
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 05/2009
1	Warfarin (Coumadin)FDA LinkGeneric 04/2009
1	Carrier Proteins (Binding Protein)IBA 03/2009
1	Heme (Haem)IBA 03/2009
1	Thyroxine (Levothyroxine)FDA LinkGeneric 08/2008
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 08/2008
1	Hemoglobins (Hemoglobin)IBA 10/2007
1	Complementary DNA (cDNA)IBA 09/2007
1	HLA-DQB1 antigen (HLA DQB1)IBA 01/2005
1	very low density lipoprotein triglycerideIBA 01/2005
1	ElementsIBA 01/2005
1	Blood Glucose (Blood Sugar)IBA 01/2005
1	Apolipoproteins E (ApoE)IBA 01/2005
1	ApolipoproteinsIBA 01/2005
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2005
1	VLDL LipoproteinsIBA 01/2005
1	HLA-DRB1*04 antigenIBA 08/2004
1	Saccharated Ferric Oxide (Venofer)FDA Link 09/2003
1	Erythropoietin FDA Link 09/2003

Therapy/Procedure

6	Therapeutics 01/2020 - 07/2002
1	Debridement 10/2009
1	Skin Transplantation (Skin Grafting) 10/2009
1	Renal Dialysis (Hemodialysis) 09/2003